Polymerase Chain Reaction (PCR)

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Dr. Kary Mullis first described polymerase chain reaction (PCR) in 1983, and won the Nobel Prize in chemistry in 1993 for his work performed on PCR. Dr. Mullis considered PCR a concept rather than a technique, but the most important aspect to his concept is that PCR literally can pull out a small piece of DNA from its context and amplify it. PCR may have a relatively recent front on science, but it certainly has brought forth …

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…Paul Rabinow. (1998). What Is PCR? In Making PCR, A Story of Biotechnology, University of Chicago Press. [Available online at: http://www/sunsite.berkeley.edu/PCR/whatisPCR.html]. (4) Gaoyan Tang, Lakshman P. Samaranayake, Hak-kong Yip, Frederick C. S. Chu, Peter C. S. Tang, and Becky P. K. Cheung. (November 2003). Direct Detection of Actinomyces spp. from Infected Root Canals in a Chinese Population: a Study using PCR-based oligonucleotides-DNA Hybridization Technique. Journal of Dentistry. Volume 31 (Issue 8), pp. 1-13.