Living With Ulcerative Colitis Ulcerative Colitis affects the Large Intestine (Colon) The colon is part of the digestive tract. When food is ingested it goes through the mouth, down the esophagus, to the stomach, then to the small intestine, which empties into the large intestine. The large intestine, averaging three feet in length, absorbs nutrients and water from food as it pushes it along toward the rectum. Once the food, now a waste product, reaches …
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