Integral proteins are the main type of proteins in membrane proteins. They not only transport and receive nutrients and ions; they also carry out most membrane functions (Alberts et al. 2004). In integral proteins, there are usually two main types of proteins, transmembrane proteins and lipid anchored proteins. The former ones extend through the lipid bilayer. A hydrophobic domain of the protein lies in the interior of the bilayer and their hydrophilic regions are exposed to …
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…Boyd, D., Manoil, C., and Beckwith, J. 1987. Determinants of Membrane Protein Topology. National Academy of Sciences 84: 8525-8529. Review: Medvedeva, T.N. 2003. The Content of Peripheral and Integral Proteins in Vertebrate Brain Microsomal Membranes. Journal of Evolutionary Biochemistry and Physiology 41: 157-161. Aman, R.A., and Wang, C.C. 1987. Identification of two integral glycosomal membrane proteins in Trypanosoma brucei. Zoological Record Plus 25: 83-92. Popular Science Source: Wikipedia. Nov. 16, 2005. Integral Protein. http://en.wikipedia.org/wiki/Integral_protein