Huntington's Background Huntington's disease is inherited as an autosomal dominant disease that gives rise to progressive, elective (localized) neural cell death associated with choleric movements (uncontrollable movements of the arms, legs, and face) and dementia. It is one of the more common inherited brain disorders. About 25,000 Americans have it and another 60,000 or so will carry the defective gene and will develop the disorder as they age. Physical deterioration occurs over a period of 10 to 20 years, …
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showed last 75 words of 1067 total
…The Neurology articles explains how HD patients have much higher deletion levels than agematched controls in the frontal and temporal lobes of the cortex, whereas the article from Times Medical Writer focuses on a possible treatment resulting from a finding of a second protein called HAP-1, that binds itself to the huntingtin molecule only in the brain. Both conclude that HD is a mutation that causes damage to brain cells further in a person's life.