Essay topic 5. 5. The neuromuscular junction as a site of disease process Proteins involved in formation of the neuromuscular junction The neuromuscular junction is a specialized junction, where a motor nerve forms its synaptic terminal with a muscle fibre, one of many fibres that make up a whole muscle. The mature neuromuscular junction is composed of three types of cells - a motor nerve terminal, a muscle fibre and a Schwann cell covering the junction. All …
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showed last 75 words of 3269 total
…amp; Squire L. R., 'Fundamental of Neuroscience', Academic Press, London, pp. 547-567 Liyanage, Y., Hoch, W., Beeson, D. & Vincetn, A. 20002, 'The agrin/muscle specific kinase pathway: New targets for autoimmune and genetic disorders at the neuromuscular junction', Muscle & Nerve, vol. 25, pp. 4-16 Reist, N. E., Werle, M. J. & McMahan, U. J. 1992, 'Agrin released by motor neurons induces the aggregation of acetylcholine receptors at neuromuscular junctions', Neuron, vol. 8, pp. 865-868