Chromatography: Validation, SOPS and System Suitability

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Equipment Validation Protocol Validation is the process to confirm that the procedure in use for a definite test is appropriate for its proposed use. Methods require validation or revalidation before the introduction of the equipment to routine use. Method validation is different than equipment validation, as method validation adheres to the methodology of the experiment, while the equipment validation refers to the apparatus being used, such as the column. The basic concept behind validation is …

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…HPLC. Oshawa, Ontario, Canada: 1995 Oxford Dictionary. Oxford Paperback Dictionary and Thesaurus. New York, USA: Oxford University Press, 2001 Skoog, Holler, Nieman. "Instrumental Analysis." Chapter 28. Harcourt Brace & Company, 1998 Stability "System Suitability Tests For Quantitative Chromatographic Methods" Retrieved April 3rd, 2005 <http://www.cvg.ca/doc/books/Stability.pdf> The Shared Research Instrumentation Facility. "Lab Manual-Page 3." HPLC. : February 4th, 2002 <http://www.gmu.edu/departments/SRIF/tutorial/hplc/hplc2.htm>