Outline I.Introduction a.What is Cancer? b.Conditions on which cancer begins. c.Two Gene Classes i.Proto-oncogenes ii.Tumor Suppressor Genes II.Signaling Systems go Wrong a.Oncogenes i.Ras family 1.Ras proteins ii.Myc family III.Tumor Suppressors Stop Working a.Malignant Cells i.TGF-B ii.DPC4 iii.p15 iv.NF-1 IV.The Clock is Struck a.The Cell Cycle i.Mitosis b.CDKs V.Conclusion How cancer develops is no longer …
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